| | | In 1951, Bing Crosby was denied a room at a Vancouver hotel for wearing too much denim. | Gossip spread to Levi Strauss, who built Bing a custom denim suit. The piece included a leather tag that mocked people who judged others by their jeans. | So one snobby hotelier led to the creation of the Canadian tuxedo. | What’s in store: | Claude was (probably) used to research biological weapons. Nvidia’s CEO has seen the future, and it’s worth $680 billion. Mindstream Picks: Global stocks slip, Celine Dion is back, and the A380 takes one step closer to retirement.
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| | | | | AI SAFETY | | | “These are chilling examples of state-sponsored biological weapons developers tapping into the rapidly advancing capabilities.” | That might seem like a sentence from a sci-fi movie pitch. But it’s actually how Andrew Weber, a senior fellow on the Council on Strategic Risks, described Anthropic’s new threat report… before the company released it to the public. | Anthropic claimed to have blocked multiple accounts from using their tools to develop bio-weapons. The company broke down five specific cases that involved AI-assisted inquiries into infectious diseases, toxins, and bio-threats like bird flu. | Now here’s the deal. The users behind this activity may have been legit scientists. They could’ve been conducting genuine research or even pressure-testing Claude’s safeguards. Who knows? The point is, Anthropic has no way of telling if these queries were ill-intended. And that’s the tricky part. | While AI can speed up life-saving research, it also has the power to expedite R&D behind biological warfare. Oof. | What Anthropic found: | Red flags: Anthropic identified 35 attempts to use AI to accelerate risky research within a 30-day review period. Five case studies: The safety report flagged inquiries into bird flu, venoms, toxins, transmissibility, and immune evasion. Sneaky workarounds: Users dodged location-based restrictions and misled Claude about their research goals to skirt the platform’s restrictions.
| Ethically ambiguous | Former CDC director, Susan Monarez, reviewed Anthropic’s findings and she didn’t mince words. | Advanced AI increases the opportunities to “let bad actors hide in plain sight, using seemingly legitimate research to create pathogens we may not see coming and may not be able to stop once released.” | Anthropic didn’t deny the danger. The company has strengthened its safeguards on newer models, and is asking other AI labs to do the same. | Because this era’s mad scientist doesn’t have an evil laugh. Just a VPN and really specific questions about immune evasion. | I’m not ready for another pandemic. - TL | Which concerns you more? | | Vote for live results and see results + opinions from yesterday at the bottom of the email. |
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| | | | What goes up but never comes down? | Find the answer at the bottom of the email! |
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| | | | OpenCode: An open-source coding agent that lets developers choose their own model provider and API key rather than locking them into one vendor. Works across terminal, desktop, IDE, and browser. Reached 120,000 GitHub stars in 2026. | CodeRabbit: Automated pull request reviewer that reads proposed code changes and leaves feedback before a human review. Free for open-source projects, and recently hit a $1.5B valuation on the back of that commitment. | Wispr Flow Notetaker: A Mac meeting recorder that captures system audio without dropping a visible bot into your call. Transcribes, identifies speakers, summarizes, and lets you search everything said. | Mistral OCR 4: A document-reading API that converts invoices, forms, and reports into structured JSON at $2 per 1,000 pages in batch mode. Built for developers automating repeatable document extraction at scale. | Unabyss: A context connector that syncs Slack, Gmail, Notion, GitHub, and other workplace apps so your AI assistant starts each conversation already knowing your project context instead of requiring a fresh briefing every time. |
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| | | | | NVIDIA | | | Jensen Huang is a founder, CEO, and (apparently) psychic. | Last week, Huang took the stage at Goldman Sachs Communacopia + Technology Conference to make a bold claim. Nvidia’s revenue would grow 70% next year, bringing the company’s top line to $680 billion. | Now, it’s common practice to gas up your brand in the land of Silicon Valley. But that’s not what’s happening here. Huang gave those same numbers to his investors last month. And he’s got the receipts to back it up. | Why Huang’s betting big: | 70%: The projected annual revenue growth, which would push Nvidia to ~$680 billion. $1 to $100: The return ratio Huang claims on Nvidia's investments. $400 billion: Nvidia's expected revenue this fiscal year.
| The shovel seller's advantage | All the major AI labs (Anthropic, OpenAI, Google) currently rely on Nvidia, even as some race to build their own chips. So Huang's claims of industry domination aren't that far off. | Plus Neoclouds, OEMs, hyperscalers, and AI-native startups all funnel data back to the company. This gives Nvidia a real-time map of where AI money and infrastructure are actually flowing. | So yes, critics call his investment deals circular. But Huang shrugs them off. | Haters will always hate the guy selling shovels in the AI gold rush. | Dang. Okay, that’s a flex. -TL |
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| | | | Space: NASA has offered new details on its upcoming Space Academy, whilst also defending the concept from criticism.
Business: Global stocks have slipped after fears over AI have become a mainstream talking point.
Music: Celine Dion returned with a concert in Paris, her first live show in 6 years. | Don’t Miss: Qantas is preparing to retire its Airbus A380, as the superjumbo moves one step closer to extinction - though Emirates offers hope for fans of the plane. |
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| | | | Image of the Day |  | Artwork submitted by Mindstream reader Yohan: “Spaghetti flavoured monster energy drink can” |
| Daily Image Prompt | The most amazing DJ set in history, taking place on the moon with a massive crowd |
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| | | | “What have you outsourced to AI that you probably shouldn't?” | First attempts at things I should struggle with - 50% ✅ | Thinking through problems properly - 23% | Opinions I should form myself - 17% | Other - tell us! 9% | Your Views: | “Writing about AI and older people and being far too optimistic - which Claude really has encouraged me to write. But optimism and anti- ageism have their limits and I have to reclaim and be more objective” - liz | “Actually it‘s all three. Which is bad.” - supamicha | “My laundry! Wash, rinse, repeat.” - rgray | Submit your opinions in our polls to be featured! |
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| Riddle Me This Answer: Your age! | #1202 Back once again for the renegade master |  | | | |
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